Detects autoantibodies targeting smooth muscle – commonly used in diagnosing autoimmune hepatitis.
Anti-smooth muscle antibody is a blood test that detects the presence of antibodies against smooth muscle. The antibody is useful in making a diagnosis of autoimmune hepatitis. A blood sample is needed. This may be taken through a vein. The procedure is called a venipuncture. No special steps are needed to prepare for this test.
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Overview:
The Anti-Smooth Muscle Antibody (ASMA) test detects autoantibodies against smooth muscle fibers. It is primarily used to help diagnose autoimmune hepatitis and other autoimmune liver diseases.
Risk Assessment / Clinical Use:
- Suspected Autoimmune Hepatitis (especially Type 1)
- Chronic unexplained liver enzyme elevation
- To differentiate autoimmune hepatitis from other liver conditions
- May also be seen in:
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Primary biliary cholangitis
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Viral hepatitis
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Some connective tissue diseases
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Normal Range:
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Negative: <1:20 (titer) or as per lab reference
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Borderline/low positive results should be clinically correlated.
Interpretation:
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Positive ASMA: Suggests autoimmune hepatitis (especially if high titer), but must be interpreted with clinical and other lab findings.
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Negative ASMA: Makes autoimmune hepatitis less likely, though not completely ruled out.
Sample Type:
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Blood sample (serum)
Frequently Asked Question
Anti Smooth Muscle Antibody (ASMA)
Detects autoantibodies targeting smooth muscle – commonly used in diagnosing autoimmune hepatitis.
Anti-smooth muscle antibody is a blood test that detects the presence of antibodies against smooth muscle. The antibody is useful in making a diagnosis of autoimmune hepatitis. A blood sample is needed. This may be taken through a vein. The procedure is called a venipuncture. No special steps are needed to prepare for this test.
Covid Safety
Assured
Free Report
Counselling