Unraveling Clotting Mechanisms: Insights from the Anti-Thrombin III Test
Antithrombin III (AT III) is a protein that helps control blood clotting. A blood test can determine the amount of AT III present in your body. A blood sample is needed. Certain medicines may affect the results of the test. Your health care provider may tell you to stop taking certain medicines or reduce their dose before the test.
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How our test process works!
Antithrombin III (AT III) is a protein that helps control blood clotting. A blood test can determine the amount of AT III present in your body. A blood sample is needed. Certain medicines may affect the results of the test. Your health care provider may tell you to stop taking certain medicines or reduce their dose before the test.
Antithrombin acts as a blood thinner and regulates blood clotting. If blood clotting happens abnormally or deep vein thrombosis occurs, then Antithrombin III test is ordered to check its level.
AT III Activity (functional test) | 80–120% of normal activity |
AT III Antigen (quantitative test) | 0.15–0.31 g/L (may vary slightly by lab) |
Interpretation of Results
| Result | Possible Interpretation |
| Low AT III Activity/Level | May indicate congenital or acquired antithrombin deficiency. Risk of thromboembolism is high. |
| Normal AT III | Rules out AT III deficiency as a cause of thrombophilia. |
| High AT III | Rare; usually not clinically significant, sometimes seen with estrogen therapy or acute inflammation. |
Specimen: Plasma (citrated)
Collection tube: Light blue-top tube (sodium citrate)
Handling:
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Sample should be processed quickly.
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Centrifuge to separate plasma.
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Freeze if delay in testing is expected.
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Frequently Asked Question
Anti thrombin III
Unraveling Clotting Mechanisms: Insights from the Anti-Thrombin III Test
Antithrombin III (AT III) is a protein that helps control blood clotting. A blood test can determine the amount of AT III present in your body. A blood sample is needed. Certain medicines may affect the results of the test. Your health care provider may tell you to stop taking certain medicines or reduce their dose before the test.
Covid Safety
Assured
Free Report
Counselling