CD34
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CD34

he subtitle of a CD34 test could vary depending on its specific purpose and context. However, a common subtitle for a CD34 test might be something like "Quantification of CD34+ Hematopoietic Stem Cells" or "Evaluation of CD34 Expression in Bone Marrow Samples." These subtitles give a brief indication of what the test measures and its relevance in clinical or research settings.

The Ibn Sina Trust
Praava Health
Dr Lal PathLabs
Omnicare Diagnostic Limited
Thyrocare Bangladesh Ltd
Brac Healthcare
Popular Diagnostic Centre Ltd
JG Healthcare
4000
4000
Sample Type
blood
Fasting Required
No
Description

A CD34 test is a type of blood test that measures the levels of CD34 cells in the bloodstream. CD34 is a protein found on the surface of certain cells, including hematopoietic stem cells, which are responsible for producing blood cells. This test is often used to assess the health of the bone marrow, where these stem cells are primarily located. It can help diagnose conditions such as leukemia, lymphoma, and other blood disorders.

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How our test process works!

Step 1

Sample Collection

Vaccinated Phlebotomists collects from syringe in the barcoded vials

Step 2

Sample Storage

Only vaccinated phelbos are assigned orders

Step 3

High Tech Facility

Lab ingests the sample into processing machines which are 100% automated

Step 4

Accurate Digital Reports

The reports are generated by the processing machines and clinically correlated by doctors

Overview

Overview

The CD34 test measures the presence and number of CD34+ cells, which are hematopoietic stem and progenitor cells. These cells play a vital role in blood cell production and are often analyzed in medical procedures like stem cell transplantation or to evaluate bone marrow function.

 

Risk assessment

Risk Assessment

CD34+ cell counts are crucial for assessing:

  1. Bone Marrow Function: Low levels may indicate bone marrow suppression or failure.
  2. Stem Cell Transplantation Readiness: Adequate CD34+ counts are necessary for successful engraftment.
  3. Cancer Diagnosis or Treatment: Levels may be monitored in patients undergoing chemotherapy or radiation therapy to assess recovery.

 

Ranges

Normal Range

  • Peripheral Blood (after mobilization): 10–20 CD34+ cells per microliter.
  • Bone Marrow: Approximately 1%–5% of total nucleated cells are CD34+.
  • Apheresis Product (stem cell harvest): ≥2 x 10⁶ CD34+ cells per kilogram of body weight is generally considered optimal for transplantation.

 

Test result interpretation

Interpretation

  • Increased CD34 Levels:
    • Effective mobilization for stem cell collection.
    • Can occur in certain hematologic malignancies.
  • Decreased CD34 Levels:
    • Bone marrow suppression or aplasia.
    • Poor response to mobilization agents.
    • Inadequate stem cell collection for transplantation.

 

Sample types

Sample Type

  • Peripheral Blood: Typically collected after mobilization with agents like G-CSF or chemotherapy.
  • Bone Marrow Aspirate: Direct assessment of bone marrow CD34+ cells.
  • Apheresis Product: Used for stem cell transplantation.

Frequently Asked Question