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Phenytoin/Dilantin/Eptoin

Monitoring Phenytoin Drug Levels in Blood for Therapeutic Management.

Sample Type

blood

Fasting Required

Description

Phenytoin is a prescription drug. It comes in three oral forms: extended-release capsule, chewable tablet, and suspension. It also comes as an injectable medication that’s given by a healthcare provider. Phenytoin oral capsule is available as the brand-name drugs Phenytek and Dilantin. It’s also available as a generic drug.

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How our test process works!

Step 1

Sample Collection

Vaccinated Phlebotomists collects from syringe in the barcoded vials

Step 2

Sample Storage

Only vaccinated phelbos are assigned orders

Step 3

High Tech Facility

Lab ingests the sample into processing machines which are 100% automated

Step 4

Accurate Digital Reports

The reports are generated by the processing machines and clinically correlated by doctors

Overview

The Phenytoin test measures the level of phenytoin, an antiepileptic medication, in the blood. Phenytoin is used to treat seizures (epilepsy) and prevent seizures during or after brain surgery. Monitoring blood levels helps ensure therapeutic efficacy and prevent toxicity.

Risk assessment

The Phenytoin test typically involves a blood sample collection, which is generally low-risk. However, as with any blood draw, there is a minimal risk of minor pain, bruising, or, rarely, infection at the puncture site.

Ranges

Therapeutic range for phenytoin levels typically falls between 10 and 20 micrograms per milliliter (mcg/mL) for most individuals. However, optimal therapeutic levels may vary depending on factors such as age, seizure type, and individual response to treatment.

Test result interpretation

Subtherapeutic levels: Below the therapeutic range may indicate inadequate seizure control and the need for dosage adjustment or additional antiepileptic medications. Therapeutic levels: Within the therapeutic range indicate effective seizure control with minimal risk of toxicity. Supratherapeutic levels: Above the therapeutic range may increase the risk of adverse effects, including dizziness, drowsiness, ataxia, nystagmus, and cognitive impairment. Prompt dose reduction or discontinuation may be necessary to prevent toxicity.

Sample types

The Phenytoin test requires a blood sample, typically collected from a vein in the arm using a needle. Serum or plasma is separated from the blood cells and analyzed in a laboratory to measure phenytoin levels.