The Serum Procalcitonin (PCT) test is used to assess the level of procalcitonin in the blood. Procalcitonin is a precursor of the hormone calcitonin, and its levels rise in response to significant bacterial infections or systemic inflammation, such as sepsis. This test helps in diagnosing and monitoring infections and differentiating between bacterial and viral infections.

Sepsis, Bacterial infections, Kidney infections, the severity of infection

Risk Status Value of PCT Normal 0 to 0.05 micrograms per litre (ug/L) Low risk of sepsis 0.05- 0.5 ug/L Possible sepsis 0.5 ug/L - 2 ug/L Moderate to high risk of sepsis Between 2 ug/L and 10 ug/L Severe sepsis 10 ug/L or greater

Interpretation of Results

• Low Procalcitonin Levels (<0.1 ng/mL):

  • Unlikely to be a bacterial infection
  • Could indicate a viral infection, non-infectious inflammation, or a mild localized infection

• Moderate to High Procalcitonin Levels (0.1-2 ng/mL):

  • Suggest bacterial infection, but further investigation is needed to confirm the type and location of the infection

• Very High Procalcitonin Levels (>2 ng/mL):

  • Strongly indicative of a severe bacterial infection or sepsis
  • Higher levels may indicate the need for urgent intervention or more intensive treatment

• Post-surgical/trauma elevation:

  • Mild to moderate increases can occur in the early phase of recovery from trauma or surgery due to inflammation.

Sample Type

• Specimen Required:
  • Blood sample (serum)
  • Collected via venipuncture (typically from the arm).