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Total Iron Binding Capacity (TIBC)
Exploring Iron Transport Dynamics for Comprehensive Health Assessment
Sample Type
blood
Fasting Required
No
Description
A TIBC (total iron-binding capacity) test is a blood test that measures your blood’s ability (capacity) to attach (bind) to iron and carry it throughout your body. Healthcare providers use it to help diagnose iron-deficiency anemia and other iron metabolism conditions. More specifically, a TIBC test shows the amount of transferrin in your blood.
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How our test process works!
Total Iron Binding Capacity (TIBC) test helps to check the iron binding capacity of a protein transferrin. It helps to diagnose excess or deficiency of iron in the blood. This test is recommended if a doctor suspects the symptoms of iron deficiency or excess such as fatigue, hair loss, paleness, delayed mental growth, irregular heart rhythm, weight loss and joints pain.
Lack of iron in diet, pregnancy or excessive menstrual blood loss can lead to iron deficiency. Genetic disorders such as sickle cell anemia, hemolytic anemia, hemochromatosis and liver damage can cause iron toxicity .
What is Total Iron Binding Capacity used for?
The TIBC Test is performed:
· To confirm anemia due to iron deficiency detected in routine checkups
· To determine excess or deficiency of iron in the body
· To determine the capacity of the blood to transport iron
The TIBC Test is performed:
· To confirm anemia due to iron deficiency detected in routine checkups
· To determine excess or deficiency of iron in the body
· To determine the capacity of the blood to transport iron
240 mcg/dL to 450 mcg/dL
Normal Range: 250 to 425µg/dL
TIBC Test results are usually interpreted in combination with other iron tests as follows:
Iron
TIBC
UIBC
Transferrin Saturation
Ferritin
Condition
Low
High
High
Low
Low
Iron Deficiency
High
Low
Low
High
High
Hemochromatosis, Hemosiderosis
Low
Low/Normal
Low/Normal
Low/Normal
High/Normal
Chronic Illness
High
Normal/Low
Low/Normal
High
High
Hemolytic Anemia
Normal/High
Normal/Low
Low/Normal
High
High
Sideroblastic Anemia
High
Normal
Low
High
Normal
Iron Poisoning
Blood
Frequently Asked Question
Common symptoms of iron overload include joint pain, fatigue and weakness, rapid weight loss, pain in chest and abdomen, joint pain, loss of sex drive, and liver damage.
Additional tests that may be prescribed in case of abnormal TIBC Test result are: · Unsaturated Iron Binding Capacity Test · Complete Blood Count · Hemoglobin and Hematocrit Test · Liver Function Test
Common signs and symptoms which appear during chronic iron deficiency include chronic unexplained fatigue and tiredness, weakness, dizziness and headaches, pale skin (pallor), and irritability.
Hemochromatosis is a condition that causes the accumulation of iron in the body to higher than normal levels. It is of two types, Hereditary Hemochromatosis and Secondary Hemochromatosis. Hereditary hemochromatosis is caused due to a genetic mutation which causes the body to absorb iron in excessive amounts from food. Secondary Hemochromatosis is commonly found in patients suffering from bleeding disorders who need multiple blood transfusions and iron accumulation from each. The symptoms of hemochromatosis in the early stages include joint pain, abdominal pain, fatigue, and weakness. In later stages, the condition may progress to cause more severe symptoms including diabetes, loss of libido, impotency, heart failure, and liver failure.
Iron deficiency is a condition which occurs if the iron content of blood falls below the normal levels. Conditions that may cause iron deficiency include: · Iron deficiency anemia · Hemolytic anemia · Malnutrition · Chronic blood loss · Bleeding disorders · Long-term infections · Pregnancy · Cancers, especially lymphoma or leukemia
There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Factors that can affect TIBC Test results include: · Anemia · Pregnancy · Oral contraceptives · Recent blood transfusion · Malnutrition · Liver diseases · Inflammation
Hemosiderosis is a condition caused due to excess accumulation of an iron-storing protein called hemosiderin in the body. Hemosiderin is formed when Red Blood Cells (RBCs) die at the end of their lifespan. Iron in the RBCs is subsequently stored in Hemosiderin to be recycled later. Hemosiderosis is caused by two factors which include internal bleeding in organs and rapid degeneration of RBCs. Accumulation of Hemosiderin may not show symptoms in the early stages. Symptoms that may appear in later stages with excess accumulation include heavy coughing which may be accompanied by blood, breathing difficulty accompanied by wheezing, fatigue, and weakness, shortness of breath during physical activity, systemic pain, rapid weight loss, and slow growth in children.
Iron overload is a condition which occurs when the iron levels of blood rise to higher than the normal levels. Conditions that can cause iron overload include: · Hemolysis · Iron poisoning due to overconsumption of iron in diet · Hemochromatosis (excessive iron accumulation) · Multiple blood transfusions · Liver diseases
Report in 12 hours
Booked 0 times
Total Iron Binding Capacity (TIBC)
Exploring Iron Transport Dynamics for Comprehensive Health Assessment
Offered by other labs
Sample Type
blood
Fasting Required
No
Description
A TIBC (total iron-binding capacity) test is a blood test that measures your blood’s ability (capacity) to attach (bind) to iron and carry it throughout your body. Healthcare providers use it to help diagnose iron-deficiency anemia and other iron metabolism conditions. More specifically, a TIBC test shows the amount of transferrin in your blood.
Covid Safety
Assured
Free Report
Counselling