TPHA
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TPHA

Swift Insights with Immunochromatographic Testing for TPHA

The Ibn Sina Trust
Praava Health
Dr Lal PathLabs
Omnicare Diagnostic Limited
Thyrocare Bangladesh Ltd
Brac Healthcare
Popular Diagnostic Centre Ltd
JG Healthcare
800
1000
20% OFF
Sample Type
blood
Fasting Required
No
Description

TPHA test is a passive hemagglutination assay based on hemagglutination of erythrocytes sensitized with T. pallidum antigen by antibodies found in the patient’s serum or plasma. It is used for both qualitative and semi-quantitative detection of anti-treponemal antibodies.

Covid Safety

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How our test process works!

Step 1

Sample Collection

Vaccinated Phlebotomists collects from syringe in the barcoded vials

Step 2

Sample Storage

Only vaccinated phelbos are assigned orders

Step 3

High Tech Facility

Lab ingests the sample into processing machines which are 100% automated

Step 4

Accurate Digital Reports

The reports are generated by the processing machines and clinically correlated by doctors

Overview
TPHA test is a passive hemagglutination assay based on hemagglutination of erythrocytes sensitized with T. pallidum antigen by antibodies found in the patient’s serum or plasma. It is used for both qualitative and semi-quantitative detection of anti-treponemal antibodies.
Risk assessment
The purpose of the TPHA test is to detect the presence of anti-syphilis spirochetes in the plasma of a patient with syphilis.
Ranges

Normal Range

  • A negative result indicates no detectable antibodies to Treponema pallidum and suggests that the individual is not currently infected with syphilis.
  • A positive result indicates the presence of antibodies and suggests a past or current infection with syphilis. However, a positive TPHA test alone cannot distinguish between active and past infection.

 

Test result interpretation

Interpretation

  • Negative: No antibodies detected, which likely means the person is not infected with syphilis.
  • Positive: Indicates that antibodies against Treponema pallidum are present, confirming past or present syphilis infection.
    • Titers may be measured for further assessment: higher titers can suggest active syphilis.
    • A positive TPHA test should be confirmed with clinical symptoms and history and may require additional tests like PCR (Polymerase Chain Reaction) or fluorescent treponemal antibody absorption (FTA-ABS) to rule out false positives.

 

Sample types

Sample Type

  • Blood Sample: The test requires a blood sample, typically drawn from a vein in the arm. The serum from the blood is then tested for the presence of Treponema pallidum antibodies.

Limitations

  • False Positives: TPHA can produce false-positive results due to other conditions (e.g., other infections, autoimmune diseases, or pregnancy).
  • False Negatives: In the early stages of syphilis or in individuals with a weak immune response, the test may not detect antibodies.

Frequently Asked Question