Report in 12 hours
Booked 0 times
TSH - Receptor antibody
Probing Thyroid Autoimmunity: Insights from the TSH-Receptor Antibody Test
Sample Type
blood
Fasting Required
No
Description
TSH receptor antibodies (TSHR-Ab) imitate the action of TSH and, by targeting these receptors, can trigger hyperthyroidism. TSHR-Abs are present in over 85% of people with Graves' disease and less commonly with Hashimoto's disease. As such, high levels of TSHR antibodies are strongly suggestive of Graves' disease.
Covid Safety
Assured
Free Report
Counselling
Recommended for You
How our test process works!
TSH receptor antibodies (TSHR-Ab) imitate the action of TSH and, by targeting these receptors, can trigger hyperthyroidism. TSHR-Abs are present in over 85% of people with Graves' disease and less commonly with Hashimoto's disease. As such, high levels of TSHR antibodies are strongly suggestive of Graves' disease.
TSH Receptor Antibody test is advised if you have symptoms of an overactive thyroid gland. These could be caused due to an autoimmune disorder known as Graves' disease.
0-1 IU/L
A decrease in the level of TSH receptor antibodies during treatment with antithyroid medications can help determine the chances of the Graves' disease going into remission.
Graves' disease (GD) is a frequent cause of hyperthyroidism and is associated occasionally with orbitopathy and dermopathy. The disease is caused by thyroid stimulating hormone receptor antibodies (TRAbs), which stimulate the thyroid stimulating hormone (TSH) receptor on the surface of thyroid follicular cells.
Blood
Frequently Asked Question
TSH Receptor Antibody testing is typically performed using a blood sample collected from the patient. The sample is analyzed in a laboratory using immunoassay techniques, such as enzyme-linked immunosorbent assay (ELISA), to detect the presence and quantify the levels of TRAbs.
There are usually no special preparations required for TSH Receptor Antibody testing. However, the healthcare provider may advise against certain medications or supplements that could interfere with the test results.
TSH Receptor Antibody testing may be ordered when a person presents with symptoms of hyperthyroidism (e.g., weight loss, rapid heartbeat, tremors) or if there are indications of autoimmune thyroid disease. It is also useful in monitoring the response to treatment in patients with Graves' disease.
The results of TSH Receptor Antibody testing indicate whether TRAbs are present in the blood and their levels. Elevated levels of TRAbs are typically seen in Graves' disease, while low or undetectable levels may be seen in other thyroid disorders.
TSH Receptor Antibody testing can be performed in medical laboratories or healthcare facilities equipped with the necessary equipment and expertise. It is typically ordered by healthcare providers, such as endocrinologists or primary care physicians, based on clinical suspicion of autoimmune thyroid disease.
TSH Receptor Antibodies are tested to diagnose autoimmune thyroid diseases, such as Graves' disease and autoimmune thyroiditis (Hashimoto's thyroiditis). They help differentiate between the various types of thyroid disorders and guide treatment decisions.
Yes, several factors can affect the results of TSH Receptor Antibody testing, including the presence of interfering substances in the blood, the timing of sample collection, and the sensitivity of the assay used. False-positive or false-negative results can occur.
Yes, TSH Receptor Antibody testing can help differentiate between Graves' disease and other thyroid disorders, such as Hashimoto's thyroiditis or subacute thyroiditis. Elevated levels of TRAbs are specific to Graves' disease.
Yes, treatment for Graves' disease may include antithyroid medications (such as methimazole or propylthiouracil), radioactive iodine therapy, or thyroidectomy (surgical removal of the thyroid gland). Treatment aims to control symptoms, normalize thyroid function, and prevent complications.
Report in 12 hours
Booked 0 times
TSH - Receptor antibody
Probing Thyroid Autoimmunity: Insights from the TSH-Receptor Antibody Test
Offered by other labs
Sample Type
blood
Fasting Required
No
Description
TSH receptor antibodies (TSHR-Ab) imitate the action of TSH and, by targeting these receptors, can trigger hyperthyroidism. TSHR-Abs are present in over 85% of people with Graves' disease and less commonly with Hashimoto's disease. As such, high levels of TSHR antibodies are strongly suggestive of Graves' disease.
Covid Safety
Assured
Free Report
Counselling