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Mannitol 20% IV (OSL)
OSL Pharma Limited
Generic: Mannitol 20%
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Mannitol 20% IV (OSL). Please consult your doctor.
CONSULT YOUR DOCTOR
Mannitol 20% IV (OSL) may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Mannitol 20% IV (OSL) is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE
Mannitol 20% IV (OSL) does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Mannitol 20% IV (OSL) is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mannitol 20% IV (OSL) may not be needed in these patients. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Mannitol 20% IV (OSL) in patients with liver disease. Please consult your doctor.
Medicine Overview of Mannitol 20% IV (OSL) 20% Infusion
Introduction
Mannitol 20% IV (OSL) is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma. Mannitol 20% IV (OSL) works by removing excess water and also relieves inflammation in the affected areas. It may be used alone or in combination with other medicines. It is administered as an injection under the supervision of a medical professional and should not be self administered. Take this medicine in the dose and duration as advised by your doctor and if...
... Show moreUses of Mannitol 20% IV (OSL)
- Acute renal failure
- Cerebral edema (accumulation of excessive fluid in the brain)
- Glaucoma
Side effects of Mannitol 20% IV (OSL)
Common
- Nausea
- Vomiting
- Headache
- Dehydration
How to use Mannitol 20% IV (OSL)
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Mannitol 20% IV (OSL) works
Mannitol 20% IV (OSL) is an inert substance with high osmotic pressure. It draws water into the kidney, which in turn increases the amount of urine production. Mannitol 20% IV (OSL) is also used to lower the pressure inside the eye or swelling around the brain.
What if you forget to take Mannitol 20% IV (OSL)?
If you miss a dose of Mannitol 20% IV (OSL), please consult your doctor.
Quick Tips
- It is given as an injection into the veins by a doctor or healthcare professional.
- Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Brief Description
Indication
Chronic bronchitis, Cerebral oedema, Oliguric phase of renal failure, Raised intracranial pressure, Renal function testing, Transurethral prostatic resection
Adult Dose
Intravenous
Oliguric phase of renal failure
Adult: 50-100 g in a 24-hr period by IV infusion. Adjust rate of administration to maintain a urine flow of at least 30-50 mL/hr.
Cerebral oedema, Reduction of raised intraocular pressure
Adult: 0.25-2 g/kg by IV infusion given over 30-60 minutes.
Renal function testing
Adult: 0.2 g/kg infused over 3-5 min.
Child Dose
Intravenous
Edema
0.25-1 g/kg IV initially; maintenance dose of 0.25-0.5 g/kg IV q4-6hr
Anuria/Oliguria
Test dose: 0.2 g/kg IV over 3-5 minutes; not to exceed 12.5 g
Discontinue if no diuresis within 2 hr
Contraindication
Pulmonary congestion or oedema; intracranial bleeding; CHF; metabolic oedema with abnormal capillary fragility; anuria due to severe renal disease; severe dehydration.
Mode of Action
Mannitol increases urinary output by inhibiting tubular reabsorption of water and electrolytes. It raises the osmotic pressure of the plasma allowing water to be drawn out of body tissues.
Precaution
Hypervolaemia; urinary tract obstruction; check for signs of fluid and electrolyte imbalance. Should not be administered with whole blood. Pregnancy, lactation.
Side Effect
Fluid and electrolyte imbalance; acidosis (with high doses). Nausea, vomiting, thirst; headache, dizziness, convulsions, chills, fever; tachycardia, chest pain; blurred vision; urticaria and hypotension or hypertension; acute renal failure; skin necrosis; thrombophloebitis.
Interaction
Increased nephrotoxicity with ciclosporin.
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