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Salazopyrin EN

Tablet-(500mg)
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Pfizer

Generic: Sulfasalazine

100 Tablets (1 Box)
৳ 2408.85
৳ 2630
8% OFF
Alternative Brands For Salazopyrin EN

Medicine Overview of Salazopyrin EN 500mg Tablet

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Introduction

Salazopyrin EN is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). Salazopyrin EN is to be taken with food. This will help you prevent an upset stomach. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Taking it with plenty of water can help you avoid kidney problems such as kidney stones. Using this medicine may cause some common side effects such as nausea, headache, loss of appetite, vomiting, diarrhea, weight loss, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms. To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problem with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check your kidney and liver functions, and blood components. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Salazopyrin EN

  • Rheumatoid arthritis
  • Ulcerative colitis
  • Crohn’s disease
  • Ankylosing spondylitis

Side effects of Salazopyrin EN

Common
  • Diarrhea
  • Gastrointestinal discomfort
  • Headache
  • Loss of appetite
  • Nausea
  • Oligospermia (low sperm count)
  • Vomiting
  • Weight loss

How to use Salazopyrin EN

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Salazopyrin EN is to be taken with food.

How Salazopyrin EN works

Salazopyrin EN is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

What if you forget to take Salazopyrin EN?

If you miss a dose of Salazopyrin EN, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Take it with food to avoid an upset stomach.
  • It may take 6-8 weeks for Sazo 500 Tablet DR to work. Keep taking it as prescribed.
  • Drink plenty of fluids while taking Sazo 500 Tablet DR in order to avoid kidney problems such as kidney stones.
  • It may cause a deficiency of folic acid. Take the supplements as suggested by the doctor.
  • Do not take Sazo 500 Tablet DR if you are allergic to sulfa drugs or aspirin.
  • It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful.
  • Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine.
  • Do not stop taking the medication suddenly without talking to your doctor.

Brief Description

Indication

Inflammatory bowel disease, Rheumatoid arthritis

Administration

Should be taken with food. Take after meals. Ensure adequate fluid intake.

Adult Dose

Oral Inflammatory bowel disease Adult: Initially, 1-2 g 4 times daily until remission occurs. Maintenance: 2 g/day in divided doses. Rheumatoid arthritis Adult: As enteric-coated tablet: Initially, 500 mg daily for the 1st wk increased by 500 mg every wk. Max: 3 g daily in 2-4 divided doses. Rectal Inflammatory bowel disease Adult: As suppository: 0.5-1 g in the morning and night, either alone or as an adjunct to oral treatment. Hepatic impairment: Avoid use.

Child Dose

Oral Inflammatory bowel disease Child: >2 yr: 40-60 mg/kg/day in divided doses. Maintenance: 20-30 mg/kg/day in divided doses. Rheumatoid arthritis Child: For polyarticular juvenile rheumatoid arthritis: >6 yr: As enteric-coated tablet: 30-50 mg/kg/day in 2 divided doses. Begin treatment with 1/4 to 2/3 of expected maintenance dose and increase wkly to reach maintenance dose in 1 mth. Max: 2 g daily. Rectal Inflammatory bowel disease Child: As suppository (may be given as divided doses): 5-8 yr: 500 mg bid; 8-12 yr: 500 mg in the morning and 1 g at night; 12-18 yr: 1 g bid.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation 10-30ml/min Admin twice daily. <10ml/min Admin once daily.

Contraindication

Hypersensitivity to sulphonamides or salicylates, porphyria, <2 yr of age, intestinal or urinary obstruction, blood dycrasias, history of leucopenia with gold therapy.

Mode of Action

Actual mechanism not determined. Sulphasalazine may have direct anti-inflammatory action in the colon. It also systemically interferes with secretion by prostaglandin synthesis inhibition.

Precaution

Hepatic/renal impairment, G6PD deficiency, allergic bronchial asthma, lactation. Lactation: Excreted into human breast milk; caution with breastfeeding, some reports of bloody stools or diarrhea in human milk fed infants of mothers taking sulfasalazine

Side Effect

>10% Anorexia (~33%),Headache (~33%),Nausea (~33%),Vomiting (~33%),Gastric distress (~33%),Apparently reversible oligospermia (~33%) <1% Skin rash,Pruritus,Urticaria,Fever,Heinz body anemia,Hemolytic anemia,Cyanosis Potentially Fatal: Severe hypersensitivity reactions, blood dyscrasias, renal and hepatic toxicity, fibrosing alveolitis.

Pregnancy Category Note

Pregnancy category: B; D if used for prolonged periods or near term; increased potential for kernicterus in the newborn

Interaction

Plasma levels reduced by rifampicin and ethambutol. Interferes with absorption of folic acid. Additive leucopaenia with gold therapy for rheumatoid arthritis. Increased haematological toxicity with azathioprine. Reduced serum levels of digoxin.

Buy Salazopyrin EN from Arogga

In Bangladesh, you can get the original Salazopyrin EN. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Salazopyrin EN in Bangladesh?

The latest price of Salazopyrin EN in Bangladesh is 2408.85৳. You can buy Salazopyrin EN at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Salazopyrin EN.
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SAFE IF PRESCRIBED
Salazopyrin EN is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
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CONSULT YOUR DOCTOR
Salazopyrin EN is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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SAFE
Salazopyrin EN does not usually affect your ability to drive.
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CAUTION
Salazopyrin EN should be used with caution in patients with kidney disease. Dose adjustment of Salazopyrin EN may be needed. Please consult your doctor. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
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UNSAFE
Salazopyrin EN is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.