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Agrippal S1
Nevian Lifescience PLC
Generic: Influenza vaccine inactivated (split virion)
Medicine Overview of Agrippal S1 Injection
বাংলা
English
Indication
Vaccine is recommended for adults and children from six months and above, especially those having high risk of associated complications, such as children, senior citizens, those who are susceptible and those who are in influenza epidemic areas.
The vaccine can induce body to generate immunoreaction against influenza virus and can be used for prevention of infection caused by, influenza virus.
Administration
Intramuscular injection (IM) on deltoid.
This vaccine should be administered before the beginning of the influenza season or as required by the epidemiological situation.
Vaccination should be repeated every year with an age-appropriate dose of vaccine of updated antigen composition.
Adult Dose
Intramuscular
Adult:
One dose of 0.5 ml. every year.
Child Dose
Intramuscular
Children over 3 years of age: one dose of 0.5 ml. every year.
Children from 6 to 36 months of age: 1 dose of 0.25 ml. every year.
For Children <9 years who have not previously been vaccinated: a 2nd dose should be given after an interval of at least 4 weeks.
Contraindication
Known anaphylactic hypersensitivity reactions to egg proteins (eggs or egg products), chicken proteins, or any other component of the vaccine including traces (formaldehyde, octoxinol 9 (Triton X-100) and neomycin).
Immunisation should not be performed during a febrile or acute illness.
Mode of Action
Influenza virus vaccine inactivated promotes immunity to influenza virus by inducing specific antibody formation.
Precaution
Since this vaccine contains traces of formaldehyde, octoxinol 9 (Triton X-100) and neomycin due to the use of these substances during production, it should be used with caution in subjects with a hypersensitivity to any of these substances. Patients with a history of Guillain-Barré Syndrome (GBS) with an onset related in time to influenza vaccination may be at increased risk of again developing GBS if given influenza vaccine. Use in pregnancy & lactation: Safety of use during pregnancy has not been established; benefits of vaccination should be weighed against potential risks. However, as an inactivated vaccine, it does not share...
... Show moreSide Effect
In children under 5 years of age, systemic reactions (e.g. fever, malaise, myalgia) may be more pronounced.
Local Reactions: Erythema (redness), swelling, pain, ecchymosis, induration.
Systemic Reactions: Fever, malaise, shivering, fatigue, headache, sweating, joint and muscular pain. These reactions usually disappear within 1-2 days without treatment.
Rarely: Neuralgia, paresthesia, convulsions and transient thrombocytopenia Allergic reactions leading to shock in rare cases. Vasculitis with transient renal involvement, in very rare cases.
Pregnancy Category Note
Use in pregnancy: Safety of use during pregnancy has not been established; benefits of vaccination should be weighed against potential risks. However, as an inactivated vaccine, it does not share the theoretical risks associated with live vaccines.
Interaction
Immunosuppressants, antineoplastics or high doses of corticosteroids may reduce response to vaccines. Increased antibody response with aldesleukin and aspirin. May possibly increase anticoagulant effects of warfarin.
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