Rimodep is a unique preparation of standardized extract ofRimodep , which is widely used as effective herbal medicine in the treatment of depression. The major active constituents ofRimodep are hypericin, hyperforin, hyperoside, quercitrin and rich in vitamin C. Jonort possesses antidepressant activity which inhibits re-uptake of neurotransmitters such as serotonin, dopamine, noradrenaline, γ-aminobutyric acid (GABA) and L-glutamate. It has also inhibiting activity of Monoamine oxidase (MAO) and Catechol-O-methyltransferase (COMT).