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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Mavixen

Name: Mavixen 100mg+40mg Tablet
Brand: Everest Pharmaceuticals Ltd.
SKU: 35903
Price: 80598 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Tablet - (100mg+40mg)

Everest Pharmaceuticals Ltd.

Generic: Glecaprevir + Pibrentasvir

Medicine Overview of Mavixen 100mg+40mg Tablet

বাংলা

English

Indication

Chronic Hepatitis C

Administration

Take with food at the same time once daily

Adult Dose

Chronic Hepatitis C Treatment-naïve adults and adolesents with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis or with compensated cirrhosis Treatment-experienced patients with HCV genotype 1 who have been previously treated with a regimen containing either an NS5A inhibitor or an NS3/4A protease inhibitor, but not both 3 tablets (ie, 300 mg/120 mg total dose) PO once daily with food Recommended duration for treatment-naïve patients Genotypes 1-6, no cirrhosis: 8 wk Genotypes 1-6, compensated cirrhosis (Child-Pugh A): 12 wk Recommended duration for treatment-experienced patients No cirrhosis Genotype 1 and NS5A inhibitor prior treatment: 16 wk Genotype 1 and NS3/4A...

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Renal Dose

Renal impairment Mild, moderate, or severe, including patients on dialysis: No dosage adjustment required

Contraindication

Severe hepatic impairment (Child-Pugh C) Coadministration with atazanavir or rifampin

Mode of Action

Glecaprevir: HCV NS3/4A protease inhibitor; necessary for the proteolytic cleavage of the HCV-encoded polyprotein (into mature forms of the NS3, NS4A, NS4B, NS5A, and NS5B proteins) and is essential for viral replication Pibrentasvir: HCV NS5A inhibitor; essential for viral RNA replication and virion assembly

Precaution

Hepatitis B virus reactivation in patients coinfected with HCV/HBV may occur

Side Effect

>10% Headache (9-17%) Fatigue (11-14%) Nausea (6-12%) 1-10% Diarrhea (3-7%) Increased bilirubin, ≥2x ULN (3.5%) Pruritus (7%)

Pregnancy Category Note

Pregnancy No adequate human data are available to establish whether or not glecaprevir/pibrentasvir poses a risk to pregnancy outcomes Animal studies No adverse developmental effects were observed when glecaprevir and pibrentasvir were administered separately during organogenesis at exposures up to 53 times (rats; glecaprevir) or 51 and 1.5 times (mice and rabbits, respectively; pibrentasvir) the human exposures at the recommended dose Lactation Unknown if distributed in human breast milk When administered to lactating rodents, glecaprevir and pibrentasvir were present in milk, without effect on growth and development observed in the nursing pups Consider the developmental and health benefits of breastfeeding...

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Interaction

Coadministration is contraindicated with rifampin or atazanavir Coadministration is not recommended with carbamazepine, efavirenz, or St John’s wort

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Mavixen

Tablet - (100mg+40mg)

Everest Pharmaceuticals Ltd.

Generic: Glecaprevir + Pibrentasvir

Additional Offers

Cashback

৳50

For purchasing above ৳5000+

Cashback

৳40

For purchasing above ৳4000+

Cashback

৳30

For purchasing above ৳3000+

Cashback

৳20

For purchasing above ৳2000+

Cashback

৳10

For purchasing above ৳1000+

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.