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Methicap

Capsule
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Bronson Laboratories (BD) Ltd

Generic: Silymarin [Milk thistle]

Alternative Brands For Methicap

Medicine Overview of Methicap Capsule

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Introduction

Methicap is a flavonoid derived from Silybum marianum, a plant commonly known as milk thistle. Methicap exhibits hepatoprotective and regenerative properties and is one of the most widely used natural compounds for the treatment of hepatic diseases worldwide, due to its antioxidant, anti-inflammatory, and antifibrotic activities. Methicap also increases hepatic levels of glutathione by raising cysteine availability, while inhibiting its catabolism to taurine that may enhance the antioxidant defense in liver. Methicap was found to oppose oxidative stress, and to slow the progression of hepatic fibrosis in alcohol-fed baboons.

Uses of Methicap

Methicap is used for the treatment of Jaundice,chronic inflammatory liver conditions, hepatic cirrhosis ,alcoholic liver damage.

Side effects of Methicap

Sometimes it cause
  • Mild digestive upset
  • Allergic reactions

How to use Methicap

Take Methicap in the dose and duration as advised by your doctor. Take Methicap orally with plenty of water. Do not chew, crush or break it.

How Methicap work

Different mechanisms of action of Methicap are as follow: Increasing the regenerative ability of the liver cells by enhancing the synthesis of DNA and RNA, as Methicap has a steroid structure; Altering the structure of the hepatocyte external membrane, that prevents entrance of the xenobiotics into the cell (poisoning with Amanita mushroom is a noteworthy example of such mechanism); Scavenging free radicals and increasing the cellular content of glutathione that leads to the inhibition of lipid peroxidation; Another mechanism of action of Methicap is modifying the transporters and receptors of cell membranes such as ABC transporters (P-gp), organic anion uptake transporter peptides (OATP), bile salt export pump, and TNF-α-dependent transporters.

What if you forget to take Methicap

If you forget to take yourMethicap , take them as soon as you remember. If it is almost time for your next dose, skip the missed dose and take it at the usual time. Avoid taking two doses at the same time.

Brief Description

Indication

It is used for the treatment and prevention of- Liver disease, (non-alcoholic & alcoholic) , Liver cirrhosis, (non-alcoholic & alcoholic) Infectious hepatitis, Drug-induced hepatitis, Liver disease secondary to diabetes mellitus, Toxicity of narcotics, Fatty liver, Jaundice.

Administration

Administered only orally as advised by the physician.

Adult Dose

1 to 3 capsule(s) should be taken into 2 to 3 times daily or medication should be continued until the relief of symptoms according to the advice of physician.

Child Dose

It should not be given to children without advice of physician. Uses for below 12 years recommended after discussion with registered physician.

Renal Dose

It should be used with caution in patients with kidney disease. Dose adjustment of Silymarin [Milk thistle] may be needed. Please consult your doctor.

Contraindication

Contraindicated in patient with a known hypersensitivity to silymarin.

Mode of Action

Different mechanisms of action of silymarin are as follow: Increasing the regenerative ability of the liver cells by enhancing the synthesis of DNA and RNA, as silymarin has a steroid structure; Altering the structure of the hepatocyte external membrane, that prevents entrance of the xenobiotics into the cell (poisoning with Amanita mushroom is a noteworthy example of such mechanism); Scavenging free radicals and increasing the cellular content of glutathione that leads to the inhibition of lipid peroxidation; Another mechanism of action of silymarin is modifying the transporters and receptors of cell membranes such as ABC transporters (P-gp), organic anion uptake transporter peptides (OATP), bile salt export pump, and TNF-α-dependent transporters.

Precaution

Over doses may mildly elevate blood pressure. Safety in young children or individuals with severe hepatic or renal disease is not known.

Side Effect

Occasionally a mild laxative effect may observe. Well tolerated in the recommended dose.

Pregnancy & Lactation Category Note

Therefore, if needed Silymarin should be taken with caution according to the physician’s advice. No established evidence is available about the use of Silymarin during pregnancy and lactation.

Interaction

Concomitant use of silymarin and butyrophenones or phenothiazines has resulted in the reduction of lipid peroxidation.

Storage Condition

Store in a cool & dry place, away from light & moisture. Keep out of reach of children.

Buy Methicap from Arogga

In Bangladesh, you can get the original Methicap. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Methicap in Bangladesh?

The latest price of Methicap in Bangladesh is ৳. You can buy Methicap at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Methicap.
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CONSULT YOUR DOCTOR
Methicap is not recommended for use during pregnancy. Controlled, long-term safety studies are lacking. Please consult your doctor.
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CONSULT YOUR DOCTOR
No experience is available about the use of Methicap .Long-term safety studies are lacking. Please consult your doctor.
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SAFE IF PRESCRIBED
Limited research on the effects of Methicap on driving ability.
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CAUTION
It should be used with caution in patients with kidney disease. Dose adjustment of Methicap may be needed. Please consult your doctor.
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CAUTION
It should be used with caution in patients with liver disease. Dose adjustment of Methicap may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.