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Dinogest 2

Tablet-(2mg)
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Nuvista Pharma Ltd

Generic: Dienogest

10 Tablets (1 Strip)
৳ 480
৳ 500
4% OFF

Medicine Overview of Dinogest 2mg Tablet

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Introduction

Dinogest 2 is used for the treatment of pelvic pain associated with endometriosis. It consists of progestin, which is similar to the female hormone and works by suppressing the production of hormone causing endometrium. Dinogest 2 can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you. Keep taking this medicine even during your menstrual periods. The most common side effects of this medicine include acne, headache, depressed mood, and breast discomfort. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, it makes your menstrual cycle irregular or you experience spotting or brown discharge in the middle of cycle. Consult with your doctor if this occurs frequently. Before taking this medicine, let your doctor know if you have ever had unexplained vaginal or uterine bleeding, or have circulatory blood disorder. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding before starting the treatment.

Uses of Dinogest 2

  • Endometriosis

Side effects of Dinogest 2

Common
  • Acne
  • Headache
  • Depression
  • Breast discomfort

How to use Dinogest 2

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dinogest 2 may be taken with or without food, but it is better to take it at a fixed time.

How Dinogest 2 works

Dinogest 2 is a progestin (female hormone). It works by suppressing the production of estradiol, a hormone that causes excessive growth of the endometrium.

Quick Tips

  • You have been prescribed Dinogest 2 for the treatment of pelvic pain associated with endometriosis.
  • Take it without any break, preferably at the same time everyday.
  • Do not use hormonal contraceptives while taking this medicine. If required, use non-hormonal methods of contraception such as condoms.
  • You may experience infrequent or irregular menstrual bleeding patterns. Consult your doctor if this bothers you.
  • Do not use Dinogest 2 if you are pregnant or breastfeeding.

Brief Description

Indication

Treatment of endometriosis.

Administration

May be taken with or without food.

Adult Dose

1 tab daily w/o interruption, taken preferably at the same time each day.

Contraindication

Hypersensitivity. Active venous thromboembolic disorder. Presence or history of arterial & CV disease (eg MI, CVA, ischemic heart disease); severe hepatic disease as long as liver function values have not returned to normal; benign or malignant liver tumors. DM w/ vascular involvement; known or suspected sex hormone-dependent malignancies; undiagnosed vag bleeding. Pregnancy. Childn prior to menarche.

Mode of Action

Dienogest is a nortestosterone derivative with no androgenic but rather an antiandrogenic activity of approximately 1/3 of that of cyproterone acetate. Dienogest binds to the progesterone receptor of the human uterus with only 10% of the relative affinity of progesterone. Despite its low affinity to the progesterone receptor, dienogest has a strong progestogenic effect in vivo. Dienogest has no significant androgenic, mineralocorticoid or glucocorticoid activity in vivo. Dienogest acts on endometriosis by reducing the endogenous production of estradiol and thereby suppressing the trophic effects of estradiol on both the eutopic and ectopic endometrium. When given continuously, dienogest leads to a hypoestrogenic, hypergestagenic endocrine environment causing initial decidualization of endometrial tissue followed by atrophy of endometriotic lesions. Additional properties eg, immunologic and antiangiogenic effects, seem to contribute to the inhibitory action of dienogest on cell proliferation.

Precaution

Obtain a complete medical history & perform physical & gynecological exam prior to initiation or reinstitution of therapy. Patients w/ history of extrauterine pregnancy or impairment of tube function, depression, chloasma gravidarum, gestational DM. Increased risk of MI or cerebral thromboembolism, DVT, pulmonary embolism; breast cancer, hepatic tumor. Adenomyosis uteri or uterine leiomyomata; recurrence of cholestatic jaundice &/or pruritus; persistent ovarian follicles. Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Lactation. Adolescents (menarche to 18 yr).

Side Effect

Increased wt; depressed mood, sleep disorder, nervousness, loss of libido, altered mood; headache, migraine; nausea, abdominal pain or distension, flatulence, vomiting; acne; alopecia; back pain; breast discomfort, ovarian cyst, hot flush, uterine/vag bleeding including spotting; asthenic conditions, irritability.

Interaction

Increased clearance w/ enzyme inducers eg phenytoin, barbiturates, primidone, carbamazepine, rifampicin; oxcarbazepine, topiramate, felbamate, griseofulvin, nevirapine, St. John's wort-containing products. Increased plasma levels w/ enzyme inhibitors eg ketoconazole, itraconazole, fluconazole; cimetidine, verapamil; erythromycin, clarithromycin, roxithromycin; diltiazem; ritonavir, saquinavir, indinavir, nelfinavir; nefazodone, fluvoxamine, fluoxetine; grapefruit juice.

Buy Dinogest 2 from Arogga

In Bangladesh, you can get the original Dinogest 2. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Dinogest 2 in Bangladesh?

The latest price of Dinogest 2 in Bangladesh is 480. You can buy Dinogest 2 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dinogest 2. Please consult your doctor.
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UNSAFE
Dinogest 2 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
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CONSULT YOUR DOCTOR
Dinogest 2 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Nonhormonal and progestin-only contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum
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SAFE
Dinogest 2 does not usually affect your ability to drive.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Dinogest 2 in patients with kidney disease. Please consult your doctor.
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CAUTION
Dinogest 2 should be used with caution in patients with liver disease. Dose adjustment of Dinogest 2 may be needed. Please consult your doctor.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.