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Evimar 13 IM Injection
Incepta Pharmaceuticals Ltd.
Generic: Polysaccharide Pneumococcal Vaccine
Medicine Overview of Evimar 13 IM Injection 0.5ml injection
বাংলা
English
Brief Description
Indications
The 0.5 mL dose of vaccine contains 25 micrograms of each of the following 23 pneumococcal polysaccharide serotypes: 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, 33F. This vaccine is recommended for active immunization against pneumococcal disease in children aged from 2 years, adolescents and adults.
Pharmacology
The vaccine is prepared from purified pneumococcal capsular polysaccharide antigens derived from the 23 serotypes that account for approximately 90% of invasive pneumococcal disease types. The following pneumococcal capsular polysaccharides are included: 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, 33F.
Dosage & Administration
Primary vaccination: Adults and children of 2 years of age or older: one single dose of 0.5 milliliter by intramuscular or subcutaneous injection. Prenovax 23 vaccine is not recommended for use in children below 2 years of age as the safety and efficacy of the vaccine have not been established and the antibody response may be poor. Special dosing: It is recommended that pneumococcal vaccine should preferably be given at least two weeks before elective splenectomy or the initiation of chemotherapy or other immunosuppressive treatment. Vaccination during chemotherapy or radiation therapy should be avoided. Following completion of chemotherapy and/or radiation...
... Show moreInteraction
Pneumococcal vaccine can be administered simultaneously with influenza vaccine as long as different needles and injection sites are used.
Contraindications
This vaccine should not be administered to:
Individuals with allergic reactions to any component of the vaccine.
Individuals with fever, acute infection or chronic diseases at the acute stage.
Individuals with uncontrolled epilepsy or other progressive diseases of the nervous system.
If only clearly needed, otherwise revaccination within 03 years is not recommended.
Side Effects
The most common adverse reactions, reported in >10% of subjects vaccinated with p neumococcal vaccine for the first time in a clinical trial, were: injection-site pain/soreness/tenderness (60.0%), injection-site swelling/ induration (20.3%), headache (17.6%), injection-site erythema (16.4%), asthenia and fatigue (13.2%), and myalgia (11.9%).
Pregnancy & Lactation
Animal studies are insufficient with respect to effects on reproductive toxicity. The vaccine should not be used during pregnancy unless clearly necessary (the potential benefit must justify any potential risk to the fetus). It is unknown whether this vaccine is excreted in human milk. Caution should be exercised when it is administered to a nursing mother. The vaccine has not been evaluated in fertility studies.
Precautions & Warnings
Delay the use of the vaccine in any significant febrile illness, other active infection or when a systemic reaction would pose a significant risk except when this delay may involve even greater risk. This vaccine should never be injected intravascularly, and precautions should be taken to make sure the needle does not enter a blood vessel. Also, the vaccine should not be injected intradermally, as injection by that route is associated with increased local reactions. If the vaccine is administered to patients who are immunosuppressed due to either an underlying condition or medical treatment (e.g., immunosuppressive therapy such as cancer...
... Show moreTherapeutic Class
Vaccines, Anti-sera & Immunoglobulin
Storage Conditions
Store refrigerated at 2° to 8°C. Protect vials from light.
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