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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Epam.
CONSULT YOUR DOCTOR
Epam is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Epam is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Epam may cause side effects which could affect your ability to drive.
Epam may cause side effects such as reduced alertness, confusion, tiredness, dizziness, poor muscle coordination and double vision. This may affect your ability to drive.
CAUTION
Epam should be used with caution in patients with kidney disease. Dose adjustment of Epam may be needed. Please consult your doctor.
CAUTION
Epam should be used with caution in patients with liver disease. Dose adjustment of Epam may be needed. Please consult your doctor.
Use of Epam is not recommended in patients with severe liver disease.
Medicine Overview of Epam 5mg Tablet
Introduction
Epam is a prescription medicine used for treating insomnia. It is generally used in combination with other medicines. It relaxes the brain and helps to treat people who have problems with their sleeping habits. Epam may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember and finish...
... Show moreUses of Epam
- Insomnia
Side effects of Epam
Common
- Dizziness
- Sedation
- Drowsiness
- Unsteadiness
- Impaired coordination
How to use Epam
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epam may be taken with or without food, but it is better to take it at a fixed time.
How Epam works
Epam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
What if you forget to take Epam?
If you miss a dose of Epam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- If you are taking Epam for the treatment of insomnia, it should not be used for more than 4 weeks.
- Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
- The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
- It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Avoid consuming alcohol as it may increase dizziness and drowsiness.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- If you have been taking this medicine for a long time, regular monitoring of blood and liver functions may be required.
- Inform your doctor if you notice a rash or other skin changes such as reddish spots or circular patches while taking this medicine.
- Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
Brief Description
Indication
Insomnia
Administration
May be taken with or without food.
Adult Dose
Oral
Short-term management of insomnia
Adult: 5 mg at night; increase to 10 mg if necessary.
Elderly: and debilitated patients: ?normal adult dose.
Child Dose
Oral
Infantile spasms
Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.
Contraindication
Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.
Mode of Action
Nitrazepam is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.
Precaution
May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy and lactation.
Side Effect
Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or double vision; tinnitus (associated with withdrawal); aspiration, increased bronchial secretion, dyspnoea.
Interaction
CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.
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