Arogga LogoArogga Home
Dotiric 0.5 - Image 1
Out Of Stock

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

Register
1406 people viewed this
info-icon
info-icon

Dotiric 0.5

tablet-(0.5mg)
brand logo
Everest Pharmaceuticals Ltd.

Generic: Dotinurad

10 Tablets (1 Strip)
৳ 55.75
৳ 60
7% OFF
Alternative Brands For Dotiric 0.5

Medicine Overview of Dotiric 0.5 0.5mg tablet

Switch language Iconবাংলা

Introduction

Gout is an inflammatory disease triggered by deposition of urate crystals secondary to longstanding hyperuricemia, and its management implies both the treatment of flares and management of hyperuricemia. Dotiric 0.5 is a selective urate reabsorption inhibitor (SURI), potently inhibits urate transporter 1 in the apical surface of renal proximal tubular cells, and has been approved for the treatment of gout and hyperuricemia.

Uses of Dotiric 0.5

For the treatment of gout and hyperuricemia.

Side effects of Dotiric 0.5

The most common side effects are gouty arthritis, limb discomfort (1% to less than 5%). (Loose stools, increased y-GTP, arthralgia, kidney stones, nephrocalcinosis, increased urinary y2 macroglobulin, increased blood creatinine, increased urine albumin/creatinine ratio, positive urine albumin) has been reported in less than 1% patients.

How to use Dotiric 0.5

_NAME_ administered orally once daily. The maintenance dose is usually 2 mg once a day and maximum dose should be 4 mg once a day.

How Dotiric 0.5 works

Dotinurad is a URAT1-selective urate reabsorption inhibitor that selectively inhibits URAT1 and inhibits urate reabsorption, thereby increasing urinary urate excretion and lowering serum urate levels. In addition, since it has weak inhibitory effects on ABCG2, OAT1 and OAT3 other than URAT143,44, it is expected to effectively lower serum uric acid levels without affecting uric acid secretion via these transporters. Thus, Dotinurad is a selective urate reabsorption inhibitor (SURI) that inhibits the reabsorption pathway mediated by URAT1 without inhibiting the uric acid secretion pathway mediated by ABCG2, OAT1 and OAT3 because of its high URAT1 selectivity.

What if you forget to take Dotiric 0.5?

Take the missed dose as soon as possible when you remember. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Never take two doses at once. Do not stop taking this medicine without your doctor's advice.

Brief Description

Indication

It is indicated for the treatment of gout and hyperuricemia.

Administration

Dotinurad is administered orally. The maximum dose should be 4 mg once a day.

Adult Dose

The usual adult dosage is 0.5 mg of Dotinurad. In the early stages of treatment with urate-lowering drugs, gouty arthritis (gout attack) may be induced by a rapid decrease in blood uric acid levels. The dose should be gradually increased to 1 mg once a day after 2 weeks and 2 mg once a day after 6 weeks. Patients should be carefully monitored after the dose is increased. If you accidentally take too much, consult your doctor or pharmacist.

Child Dose

Not recommended for children.

Renal Dose

Consider treatment with other agents. Since this drug acts in the renal proximal tubule, its efficacy may be reduced depending on the degree of renal dysfunction. In particular, administration of this drug should be avoided in patients with oliguria or anuria, as its efficacy cannot be expected.

Contraindication

Dotinurad is contraindicated in patients with known hypersensitivity to the drug component.

Mode of Action

Dotinurad is a URAT1-selective urate reabsorption inhibitor that selectively inhibits URAT1 and inhibits urate reabsorption, thereby increasing urinary urate excretion and lowering serum urate levels. In addition, since it has weak inhibitory effects on ABCG2, OAT1 and OAT3 other than URAT143,44, it is expected to effectively lower serum uric acid levels without affecting uric acid secretion via these transporters. Thus, Dotinurad is a selective urate reabsorption inhibitor (SURI) that inhibits the reabsorption pathway mediated by URAT1 without inhibiting the uric acid secretion pathway mediated by ABCG2, OAT1 and OAT3 because of its high URAT1 selectivity.

Precaution

This drug is a uric acid-lowering drug and lowering the blood uric acid level at the onset of gouty arthritis (gouty attack) may exacerbate gouty arthritis (gouty attack). If gouty arthritis (gout attack) is observed before administration of this drug, administration of this drug should not be started until the symptoms subside. In addition, if gouty arthritis (gouty attack) occurs during administration of this drug, administration should be continued without changing the dose of this drug and colchicine, non-steroidal anti-inflammatory drugs, corticosteroids etc. may be administered depending on the symptoms. Use together.

Side Effect

Common side effects are: gouty arthritis, limb discomfort (1% to less than 5%). (Loose stools, increased y-GTP, arthralgia, kidney stones, nephrocalcinosis, increased urinary y2 macroglobulin, increased blood creatinine, increased urine albumin/creatinine ratio, positive urine albumin) has been reported in less than 1% patients.

Pregnancy Category Note

During pregnancy, Dotinurad should only be treated if the therapeutic benefits are judged to outweigh the risks.

Interaction

Pyrazinamide: The effect of this drug may be weakened. Pyrazinamide is known to suppress uric acid secretion in renal tubules and may antagonize the promotion of uric acid excretion by this drug. Salicylic acid preparations Aspirin: Salicylic acid preparations are known to suppress uric acid excretion and may antagonize the promotion of uric acid excretion by this drug.

Buy Dotiric 0.5 from Arogga

In Bangladesh, you can get the original Dotiric 0.5. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Dotiric 0.5 in Bangladesh?

The latest price of Dotiric 0.5 in Bangladesh is 55.75৳. You can buy Dotiric 0.5 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

Rocket Icon
CAUTION
Caution is advised when consuming alcohol with Dotiric 0.5 Please consult your doctor.
Rocket Icon
CONSULT YOUR DOCTOR
During pregnancy, Dotiric 0.5 should only be treated if the therapeutic benefits are judged to outweigh the risks.
Rocket Icon
CONSULT YOUR DOCTOR
This drug is excreted in breast milk. Consult your doctor before breastfeeding.
Rocket Icon
CAUTION
It is not known whether Dotiric 0.5 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Rocket Icon
CONSULT YOUR DOCTOR
Consider treatment with other agents. Since this drug acts in the renal proximal tubule, its efficacy may be reduced depending on the degree of renal dysfunction. In particular, administration of this drug should be avoided in patients with oliguria or anuria, as its efficacy cannot be expected.
Rocket Icon
CAUTION
Careful follow-up should be performed. Serious liver damage has been observed with other uricosuric agents.

You May Also Like

see all

More from Everest Pharmaceuticals Ltd.

see all
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.