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I-Penam 500 Injection

Injection-(500mg/vial)
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Incepta Pharmaceuticals Ltd.

Generic: Meropenem

1 Injection
৳ 630
৳ 700
10% OFF
Alternative Brands For I-Penam 500 Injection

Medicine Overview of I-Penam 500 Injection 500mg/vial Injection

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Introduction

I-Penam 500 Injection is an antibiotic that fights bacteria. It is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood and brain (eg. meningitis). It works by killing the bacteria that cause these problems. However, it will not treat a viral infection. I-Penam 500 Injection is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip/infusion or by direct injection into a vein, under the supervision of a healthcare professional. The dose depends on what type of infection you have, where it is in the body and how serious it is. You should have your injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen. Some people may develop side effects like nausea, vomiting, diarrhea, rash or local redness and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. Before starting treatment with this medicine, you should tell your doctor if you have epilepsy (seizures), liver or kidney problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your blood cell count and kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by your doctor.

Uses of I-Penam 500 Injection

  • Severe bacterial infections

Side effects of I-Penam 500 Injection

Common
  • Injection site reactions (pain, swelling, redness)
  • Nausea
  • Vomiting
  • Headache
  • Rash

How to use I-Penam 500 Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How I-Penam 500 Injection works

I-Penam 500 Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

What if you forget to take I-Penam 500 Injection?

If you miss a dose of I-Penam 500 Injection, please consult your doctor.

Quick Tips

  • I-Penam 500 Injection is an antibiotic that's usually only given in the hospital for serious infections.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.

Brief Description

Indication

Cystic fibrosis, Intra-abdominal infections, Meningitis, Skin and skin structure infections, Diabetic foot infection

Administration

IV Administration Administer IV infusion over 15-30 minutes; administer IV bolus over 3-5 minutes

Adult Dose

Intravenous Intra-abdominal infections Adult: 1 g 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Skin and skin structure infections Adult: 500 mg 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Cystic fibrosis, Meningitis Adult: 2 g 8 hrly infused over approx 15-30 min. Susceptible infections Adult: 0.5-1 g 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Hepatic impairment: No dosage adjustment needed.

Child Dose

Children: IV 60 mg/kg/day, max 3 g/day q8h 120 mg/kg/day meningitis, max 6 g/day q8h Intravenous Intra-abdominal infections Child: >3mth ?50 kg: 20 mg/kg 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Max: 1000 mg. Skin and skin structure infections Child: >3 mth ?50 kg: 10 mg/kg 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Max: 500 mg. Cystic fibrosis, Meningitis Child: >3 mth ?50 kg: 40 mg/kg 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Max: 2 g. Susceptible infections Child: >3 mth ?50 kg: 10 or 20 mg/kg 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min.

Renal Dose

Renal impairment: CrCl (ml/min) 26-50 Usual dose 12 hrly. 10-25 Half the usual dose 12 hrly. <10 Half the usual dose 24 hrly.

Contraindication

Hypersensitivity to meropenem, other carbapenems. History of anaphylactic reaction to β-lactams (e.g. penicillins, cephalosporins).

Mode of Action

Meropenem is a synthetic carbapenem beta-lactam antibiotic that exerts its bactericidal activity by inhibiting bacterial cell wall synthesis in gm+ve and gm-ve bacteria through binding to several penicillin-binding proteins (PBPs).

Precaution

Patient w/ underlying CNS disorders (e.g. brain lesions, history of seizures. Not recommended for treatment of MRSA. Renal impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor for signs of anaphylaxis during 1st dose. Periodically assess renal, hepatic, and haematopoietic functions during prolonged therapy. Lactation: Unknown whether drug is excreted in breast milk; use with caution

Side Effect

1-10% Constipation (1-7%),Diarrhea (4-5%),Nausea or vomiting (1-4%),Rash (2-3%; includes diaper-area moniliasis in pediatric patients),Headache (2%),Inflammation at injection site (2%),Sepsis (2%),Oral moniliasis (≤2% in pediatric patients),Bleeding (1.2%),Apnea (1%),Constipation (1%),Glossitis (1%),Injection-site reaction (1%),Phlebitis or thrombophlebitis (1%),Pruritus (1%),Septic shock (1%) <1% Agranulocytosis,Angioedema,Erythema multiforme,Hypersensitivity reaction,Hypokalemia,Leukopenia,Neutropenia,Pleural effusion,Stevens-Johnson syndrome,Toxic epidermal necrolysis disorders or renal impairment. Potentially Fatal: Anaphylaxis; pseudomembranous colitis; Stevens-Johnsons sydrome.

Interaction

Increased plasma concentration w/ probenecid. May decrease plasma levels of valproic acid thus, increasing the risk of seizures.

Buy I-Penam 500 Injection from Arogga

In Bangladesh, you can get the original I-Penam 500 Injection. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of I-Penam 500 Injection in Bangladesh?

The latest price of I-Penam 500 Injection in Bangladesh is 630৳. You can buy I-Penam 500 Injection at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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SAFE
Consuming alcohol with I-Penam 500 Injection does not cause any harmful side effects.
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SAFE IF PRESCRIBED
I-Penam 500 Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
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SAFE IF PRESCRIBED
I-Penam 500 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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CONSULT YOUR DOCTOR
It is not known whether I-Penam 500 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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CAUTION
I-Penam 500 Injection should be used with caution in patients with kidney disease. Dose adjustment of I-Penam 500 Injection may be needed. Please consult your doctor.
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SAFE IF PRESCRIBED
I-Penam 500 Injection is safe to use in patients with liver disease. No dose adjustment of I-Penam 500 Injection is recommended.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.