Unveiling Hepatitis B Acute Infections: The Significance of Anti-HBc IgM Testing
HBsAg test is a blood test that detects hepatitis B surface antigen (HBsAg). HBsAb is a protein on the surface of the hepatitis B virus. High levels of HBsAg typically indicate an active hepatitis B virus infection. HBsAg is a part of the outer layer of a hepatitis B virus cell. The center of the cell contains the viral DNA
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Overview
The Hepatitis B Surface Antigen (HBsAg) ELISA test is used to detect the presence of the Hepatitis B virus (HBV) in the blood. It helps diagnose acute or chronic Hepatitis B infection and is also used for screening blood donors and monitoring HBV treatment.
Risk Assessment
- High-Risk Groups for HBV infection include:
- Healthcare workers
- People with multiple sexual partners or unprotected sex
- IV drug users
- Individuals receiving blood transfusions (rare due to screening)
- Infants born to HBV-infected mothers
- Patients undergoing dialysis
- Household contacts of infected individuals.
Normal Range
- Negative / Non-Reactive (<1.0 S/CO or IU/mL depending on assay type)
- Positive / Reactive (>1.0 S/CO or IU/mL)
- Different laboratories may have slightly different cutoff values, so results should be interpreted in context.
Interpretation of Results
| Result | Meaning | Further Action |
|---|---|---|
| Negative (Non-reactive) | No Hepatitis B virus detected | No infection, but vaccination may be needed |
| Positive (Reactive) | Active Hepatitis B infection (Acute or Chronic) | Further testing (HBV DNA, ALT levels, HBeAg) required |
| Borderline/Indeterminate | Possible low antigen presence or false positive | Repeat test or confirm with HBV DNA test |
- A positive result may indicate acute infection, chronic carrier state, or recent vaccination (temporary presence).
Sample Type
- Blood sample (Serum or Plasma)
- Collection Method: Venipuncture (blood drawn from a vein)
- Storage & Transport: Typically stored at 2–8°C, if not tested immediately.
Frequently Asked Question
HBs Ag (ELISA)
Unveiling Hepatitis B Acute Infections: The Significance of Anti-HBc IgM Testing
HBsAg test is a blood test that detects hepatitis B surface antigen (HBsAg). HBsAb is a protein on the surface of the hepatitis B virus. High levels of HBsAg typically indicate an active hepatitis B virus infection. HBsAg is a part of the outer layer of a hepatitis B virus cell. The center of the cell contains the viral DNA
Covid Safety
Assured
Free Report
Counselling