The HLA-B27 genotyping test is a genetic test used to identify the presence of the HLA-B27 allele, a specific gene variant in the human leukocyte antigen (HLA) system. This allele is associated with a higher risk of developing certain autoimmune a...
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HLA-B27 Genotyping
Purpose of HLA-B27 Genotyping Test0:45: Test Procedure1:30: Symptoms Associated with Abnormalities2:15: Importance of Specialist Consultation2:45: Conclusion
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Description
Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells. HLA-B27 is strongly associated with ankylosing spondylitis and other associated inflammatory diseases, such as psoriatic arthritis, inflammator.
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