Precision in Autoimmune Diagnosis: Exploring the P-ANCA Test
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Sample Type:
blood
Fasting Required:
No
Description
p-ANCA, or MPO-ANCA, or perinuclear anti-neutrophil cytoplasmic antibodies, are antibodies that stain the material around the nucleus of a neutrophil. They are a special class of anti-neutrophil cytoplasmic antibodies. This pattern occurs because the vast majority of the antigens targeted by ANCAs are highly cationic (positively charged) at pH 7.00