
A Biomarker for Early Detection of Renal Tubular Injury
This test measures the level of transferrin, a plasma protein, in urine. Elevated urinary transferrin indicates early kidney damage or glomerular dysfunction, often before albumin appears in urine. It’s used for monitoring kidney health, especially in high-risk patients like those with diabetes or hypertension.
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Overview:
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Transferrin is a glycoprotein responsible for iron transport in the blood.
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Normally, urine contains little to no transferrin. Its presence in urine can indicate glomerular damage or early kidney disease, especially before albumin appears.
Purpose / Indication:
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Detect early kidney damage (especially in diabetic nephropathy).
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Evaluate glomerular permeability.
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Monitor kidney disease progression.
Risk Assesment:
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Non-invasive; no significant risk.
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Ensure proper urine collection to avoid contamination.
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False positives possible with menstrual blood contamination, urinary tract infection, or vigorous exercise.
Normal Range:
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Random urine: < 0.1 mg/dL
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24-hour urine: < 0.1–0.3 mg/day (lab-specific reference may vary)
Interpretation:
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Normal: Transferrin absent or very low.
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Mild elevation: Early glomerular damage.
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High levels: Significant kidney injury, glomerulonephritis, or proteinuria.
Sample Type:
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Urine (usually a random or 24-hour collection).
Frequently Asked Question
Transferrin Urine
A Biomarker for Early Detection of Renal Tubular Injury
This test measures the level of transferrin, a plasma protein, in urine. Elevated urinary transferrin indicates early kidney damage or glomerular dysfunction, often before albumin appears in urine. It’s used for monitoring kidney health, especially in high-risk patients like those with diabetes or hypertension.
Covid Safety
Assured
Free Report
Counselling
