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Edimox 250
Gaco Pharmaceuticals(G.A Company Ltd)
Generic: Acetazolamide
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Edimox 250. Please consult your doctor.
CONSULT YOUR DOCTOR
Edimox 250 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Edimox 250 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Doses of up to 1000 mg daily produce low levels in milk and would not be expected to cause any harmful effects in breastfed babies.
UNSAFE
Edimox 250 may cause side effects which could affect your ability to drive.
.Edimox 250 can occasionally cause short-sightedness, drowsiness or confusion which may affect your ability to drive.
CAUTION
Edimox 250 should be used with caution in patients with kidney disease. Dose adjustment of Edimox 250 may be needed. Please consult your doctor.
Use of Edimox 250 is not recommended in patients with severe kidney disease.
CAUTION
Edimox 250 should be used with caution in patients with liver disease. Dose adjustment of Edimox 250 may be needed. Please consult your doctor.
Use of Edimox 250 is not recommended in patients with severe kidney disease.
Medicine Overview of Edimox 250mg Tablet
Introduction
Edimox 250 is a medicine used to reduce pressure in the eyes. This pressure can be caused by or lead to an illness called glaucoma. If the pressure in your eye is too high it can damage your sight. Edimox 250 works by decreasing the amount of fluid inside the eye. You can take Edimox 250 with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. Use...
... Show moreUses of Edimox 250
- Glaucoma
Side effects of Edimox 250
Common
- Headache
- Dizziness
- Tiredness
- Frequent urge to urinate
- Tingling sensation of extremity
- Numbness of extremity
- Loss of appetite
- Excitement
- Feeling sick
- Diarrhea
- Taste change
- Flushing (sense of warmth in the face, ears, neck and trunk)
How to use Edimox 250
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Edimox 250 may be taken with or without food, but it is better to take it at a fixed time.
How Edimox 250 works
Edimox 250 is a carbonic anhydrase inhibitor. It works in glaucoma by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure. It also acts on the kidneys to remove extra water and electrolytes through urine to relieve fluid retention and oedema (swelling). In epilepsy, it relieves seizures (fits) by stabilizing electrical activity in the brain.
What if you forget to take Edimox 250?
If you miss a dose of Edimox 250, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Edimox 250 helps lower high pressure in the eye and reduce the risk of vision loss.
- Usually used in combination with other anti-glaucoma medications.
- Take it as per dose and duration suggested by your doctor.
- Use caution while driving or doing anything that requires concentration as Edimox 250 can make you very drowsy.
- It may cause a tingling sensation in hands and feet. Take potassium-rich foods (banana and coconut water), and get potassium levels checked regularly.
Brief Description
Indication
Adult: PO Diuresis 250-375 mg/day.
Glaucoma; Epilepsy 250-1,000 mg/day.
Prophylaxis of high altitude sickness 500-1,000 mg/day.
Epilepsy
>12 years
Tablet: 8-30 mg/kg/day PO qDay or divided q6-12 hr; not to exceed 30 mg/kg/day or 1 g/day
Acute Altitude Sickness >12 years
Immediate release: 500-1000 mg/day PO divided q8-12hr
Hepatic impairment: Contraindicated in marked hepatic impairment.
Administration
Concomitant use w/ high-dose aspirin may cause anorexia, tachypnoea, lethargy, metabolic acidosis, coma and death. May increase serum levels of phenytoin, resulting to increased risk of osteomalacia. May decrease serum concentrations of primidone. Additive effects w/ other carbonic anhydrase inhibitors. May increase the effects of folic acid antagonists. May decrease urinary excretion of amphetamine and quinidine. May prevent the urinary antiseptic effect of methenamine. May increase lithium excretion. Increased risk of renal calculus formation w/ Na bicarbonate. May increase ciclosporin levels.
Adult Dose
Potassium supplements may be required. Impaired hepatic or renal function; diabetes. Monitor plasma electrolytes and blood count regularly. IM route is not recommended. Caution when driving or operating machinery. Elderly.
Lactation: Enters breast milk; not recommended
Renal Dose
Acetazolamide specifically inhibits the enzyme carbonic anhydrase which catalyses the reversible reaction involving the hydration of CO2 and dehydration of carbonic acid. It increases the excretion of HCO3 ions and as well as Na and K leading to alkaline diuresis. Carbonic anhydrase is also inhibited in the CNS to retard abnormal and excessive discharge from neurons.
Contraindication
<12 years: Safety and efficacy is not established
Mode of Action
Should be taken with food.
Precaution
Glaucoma, Epilepsy, Idiopathic intracranial hypertension, Altitude sickness
Side Effect
Renal impairment: Contraindicated in marked renal impairment.
Pregnancy Category Note
Drowsiness, paraesthesia, ataxia, dizziness, thirst, anorexia, headache; confusion, malaise, depression; GI distress, metabolic acidosis, polyuria, hyperuricaemia, renal calculi, nephrotoxicity, hepatic dysfunction.
Potentially Fatal: Rarely, skin reactions or blood dyscrasias.
Interaction
Hypersensitivity to sulphonamides; sodium or potassium depletion, hepatic insufficiency; hepatic cirrhosis; hyperchloraemic acidosis; severe renal impairment; severe pulmonary obstruction; chronic noncongestive angle-closure glaucoma; adrenocortical insufficiency. Pregnancy, lactation.
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