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Vitamin D 1,25 Dihydroxy
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Vitamin D 1,25 Dihydroxy

Measures the active form of vitamin D to assess calcium, phosphate & bone metabolism.

The Ibn Sina Trust
Praava Health
Dr Lal PathLabs
Omnicare Diagnostic Limited
Thyrocare Bangladesh Ltd
Brac Healthcare
Popular Diagnostic Centre Ltd
JG Healthcare
Sample Type
blood
Fasting Required
No
Description

This blood test measures the level of 1,25-dihydroxyvitamin D, the active form of vitamin D in the body. Unlike 25-hydroxyvitamin D (which is commonly tested for general vitamin D status), this test evaluates the active hormonal form that regulates calcium and phosphate metabolism, especially in patients with kidney disorders, parathyroid dysfunction, or abnormal calcium levels.

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How our test process works!

Step 1

Sample Collection

Vaccinated Phlebotomists collects from syringe in the barcoded vials

Step 2

Sample Storage

Only vaccinated phelbos are assigned orders

Step 3

High Tech Facility

Lab ingests the sample into processing machines which are 100% automated

Step 4

Accurate Digital Reports

The reports are generated by the processing machines and clinically correlated by doctors

Overview

Overview:

The Vitamin D 1,25-dihydroxy (calcitriol) test measures the active form of vitamin D in the blood. Calcitriol is produced in the kidneys from 25-hydroxyvitamin D, under the regulation of parathyroid hormone (PTH). This form is responsible for calcium and phosphate metabolism, bone health, and immune function.

 

Risk Assessment

Clinical Indications / Risk Assessment:

  • Unexplained hypercalcemia or hypocalcemia
  • Chronic kidney disease (CKD)
  • Parathyroid disorders
  • Granulomatous diseases (e.g., sarcoidosis, tuberculosis)
  • Lymphoma or other malignancies
  • Suspected vitamin D-dependent rickets type I or II
Normal Range

Normal Range:

15–60 pg/mL (picograms per milliliter)
(This may vary slightly by lab and method used)

 

Interpretation

Interpretation:

Result Interpretation
Low CKD (due to decreased 1-alpha hydroxylase activity), hypoparathyroidism, vitamin D–dependent rickets type I
High Sarcoidosis, tuberculosis, lymphoma (due to ectopic 1-alpha hydroxylase), primary hyperparathyroidism, excessive supplementation with calcitriol.

 

Sample Type

Sample Type:

  • Specimen: Venous blood

  • Tube: Typically a red-top or SST (serum separator) tube

  • Handling: Serum is separated and frozen if not analyzed immediately, as the analyte is sensitive.

Frequently Asked Question